A significant global investigation indicates that markedly low testosterone levels may indicate an increased long-term risk of cancer in males. Researchers involved in the Androgens In Men Study examined data from over 26,000 men participating in 11 extensive studies conducted in Australia, the United States, and Europe. Findings reveal that men with testosterone levels in the lowest quintile face an 18% greater likelihood of cancer-related mortality compared to those in the highest quintile. The risk for cancer began to rise when testosterone fell below 8.6 nmol/L. The research team emphasizes that these results do not establish a direct causal relationship between testosterone and cancer, advising men to pursue medical assessment rather than self-administer hormone treatments.
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