The official trailer for Best Medicine Season 2 brings Dr. Martin Best back for another round of unusual patients, complicated relationships, and the personal drama he would much rather avoid.
Josh Charles returns as the brilliant former Boston surgeon whose blunt bedside manner hasn't exactly endeared him to the residents of his small coastal town. While Martin can handle just about any medical mystery that walks through his door, navigating the increasingly complicated lives of the people around him remains another matter entirely. And this season, even his future in town may be uncertain.
Best Medicine Season 2 premieres September 22, 2026, on FOX and streams the next day on Hulu.
